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Immunization with SARS Coronavirus Vaccines Leads to Pulmonary Immunopathology on Challenge with the SARS Virus

 It is imperative to read this animal study done in April 2012 by the  Department of Microbiology and Immunology, The University of Texas Medical Branch, Galveston, Texas  and other branches of the University of Texas. The study conclusion : "These SARS-CoV vaccines all induced antibody and protection against infection with SARS-CoV. However, challenge of mice given any of the vaccines led to occurrence of Th2-type immunopathology suggesting hypersensitivity toSARS-CoV components was induced. Caution in proceeding to application of a SARS-CoV vaccine in humans is indicated."

The vaccines appear to be effective in producing antibodies, but when  exposure to the Sars-CoV virus hypersensitivity was the results. The immune system overreacts and may cause additional damage to the lungs. See attached pdf.

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